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KMID : 0043320080310080970
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Archives of Pharmacal Research
2008 Volume.31 No. 8 p.970 ~ p.972
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A New Chromone Glycoside from Rhododendron spinuliferum
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Chen Gang
Jin Hui Zi
Li Xue Feng
Zhang Qi
Shen Yun Heng
Yan Shi Kai
Zhang Wei Dong
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Abstract
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A new chromone glycoside, 3,5,7-trihydroxylchromone-3-O--L-arabinopyranoside (1), together with quercetin (2), (+)-catechin (3), (-)-epi-catechin (4) were isolated from the aerial parts of Rhododendron spinuliferum. The structure of 1 was elucidated on the basis of spectroscopic and 2D-NMR spectral analysis. In addition, 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.
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KEYWORD
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Rhododendron spinuliferum, Chromone, 3, 5, 7-Trihydroxylchromone-3-O--L-arabinopyranoside, Nitric oxide (NO) production
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